Chronotherapeutics and Drug Delivery: A Review.
Author (s): Dhananjay Panigrahi
Associate Director, Integrated Product Development, Dr. Reddy’s Laboratories Ltd., Hyderabad
This writing aims at knowledge of time matched delivery of drugs for obtaining optimum therapeutic benefits of drug. The human body follows the day and night adaptations known as biological clock. The biological clock follows the main rhythm known as circadian rhythm. Chronotherapeutics is treatment method in which in vivo drug availability is timed to meet rhythms of disease, in order to optimize therapeutic outcomes and minimize side effects. This approach is highly scientific to design the drug delivery systems.
Keywords: circadian rhythm,Chronotherapeutics,drug delivery systems