2021, Volume 2 Issue 2 – Article 2

Review

Theranostics and its Potential Applications in Healthcare Management

Author (s): Subrat Kumar Bhattamisra1,*,Teng Carine2, Amanda Tan Yee Mun2, Brandon Ko Wei Kwong2, Audrey Lim Jia Yee2, Andrea Yap Xin Wei2, Muhammad Haris Hakimi bin Ahmad Bakri2, Chai Shereen2, Bibhu Prasad Panda3, Hira Choudhury4, Manisha Pandey4

1Department of Life Sciences, School of Pharmacy, International Medical University, Bukit Jalil 57000, Kuala Lumpur, Malaysia

2School of Pharmacy, International Medical University, Bukit Jalil 57000, Kuala Lumpur, Malaysia

3Department of Pharmaceutical Technology, School of Pharmacy, Taylor’s University, Lakeside Campus, No 1, Jalan Taylor’s, 47500 Subang Jaya, Selangor, Malaysia

4Department of Pharmaceutical Technology, School of Pharmacy, International Medical University, Bukit Jalil 57000, Kuala Lumpur, Malaysia


Abstract:

Theranostics emerges as a targeted, efficient and safe pharmacotherapy in the field of medicine. It is a novel concept involving the use of a single agent for both diagnostic and therapeutic applications, thus providing a cost-effective treatment protocol. By promoting patient-centered care, it enables a change from conventional medicine to personalised medicine. In the present review, various theranostics agents and their potential applications in disease management are described.  An extensive literature search was conducted using keywords “Theranostic”; “Theranostic agents”; “Nuclear medicine”; “Nanotechnology”; Theranostics application” in the public domains of Science Direct, PubMed and Google Scholar. The articles were shortlisted based on their usefulness for the review. Theranostic agents such as nanoparticles, nuclear medicine, genetic materials, antibodies and antibody-related therapeutics are used in the management of diseases. The theranostic agents have been used for the diagnosis, delivery of therapeutic agents and monitoring the patients in response to the treatment of cancers, neuronal diseases, atherosclerosis, and diabetes mellitus. The emerging theranostics approach has become a predictive, preventive, personalised and participatory medicine in healthcare management with the potential to improve the quality of clinical care and treatments.

Keywords: Theranostics, nanotechnology, genetic material, nuclear medicines, antibodies.